Dragon is the world-wide most used application for the calculation of molecular descriptors. Its new version, Dragon 7.0, provides an improved user interface, new descriptors and additional features such as the calculation of fingerprints and the support for disconnected structures.
An introductory tutorial is available, with a brief walk-through of Dragon's main features.
Browse the following sections to learn more about Dragon. An extension allowing the usage of Dragon inside KNIME workflows is also available, please visit its section for more details.
Standalone application for Windows and Linux platforms
Supported platforms: Microsoft Windows (7, 8.1 and 10) and Linux (Fedora Core 23, Ubuntu 14.04).
Academic and commercial licenses are available with different options. Check the underlying section for more details.
The standard academic license fee is 900 €. Owners of a Dragon 6 academic license can upgrade to Dragon 7 for a special fee of 300 €. For commercial licenses and upgrades please contact us or ask a quotation from your private area.
How to get it
Ask a quotation from your private area (requires registration) or contact us directly by email. The purchased software is delivered by a safe download procedure from our website.
Dragon 7.0 calculates 5,270 molecular descriptors, organized in different logical blocks as in the previous versions. Blocks are further divided into sub-blocks to make management, selection, and analysis of descriptors easier. Following, the summary of molecular descriptors blocks calculated by Dragon 7.0 is reported. The complete list of all 5,270 calculated descriptor is also available.
|Block no.||Block name||Descriptors|
|4||Walk and path counts||46|
|7||2D matrix-based descriptors||607|
|12||Edge adjacency indices||324|
|14||3D matrix-based descriptors||99|
|20||Randic molecular profiles||41|
|21||Functional groups count||154|
|23||Atom-type E-state indices||172|
|25||2D Atom Pairs||1596|
|26||3D Atom Pairs||36|
Dragon 7.0 provides the calculation of hashed molecular fingerprints.
It calculates path based and extended connectivity fingerprints (ECFP). Path based fingerprints are generated identifying all linear paths of the molecule while ECFP are generated exhaustively identifying all circular fragments grown radially from each heavy atom of the molecule.
Both fingerprint types are calculated defining a set of options like the fingerprint size, the minimum and maximum length of the identified fragments and an extensive list of atom properties to be considered in order to differentiate fragments (e.g. atom type, aromaticity, formal charge, connectivity and bond order). The full customization of fingerprints allows to obtain the most suitable solutions for any task (modelling, similarity screening etc.).
Along with the fingerprints, Dragon 7.0 also calculates the full list of molecular fragments identified in the processed dataset, and provides them as SMARTS string, together with a set of useful statistics.
Dragon is used as a part of several QSAR modelling applications and suites, here you can find a list of some projects and applications that use Dragon for the calculation of molecular descriptors. Dragon is also widely used in scientific studies, a partial list of scientific papers where Dragon has been used and cited is available.
Dragon 7.0 is available with academic or commercial licenses.
Academic licenses are provided to universities, under such licenses Dragon can be used for any research from which any resulting intellectual property remains in the public domain, but any commercial use is forbidden. Academic licenses are permanent, and the user has no access to any major software update, and access to minor updates only for the first year. They allow to install and use Dragon on a maximum of three computers. The standard Academic license is provided at a special price (900 €) to foster and to support academic research.
Commercial licenses are provided with different options in order to meet the specific needs of the user:
Owners of previous Dragon 6 licenses can upgrade to Dragon 7 with a special discounted fee. Owners of Dragon licenses older than version 6 can not upgrade and should purchase the software at its full price. The upgrade fee from previous Dragon 6 academic licenses is 300 €.
For the prices of commercial licenses and upgrades please contact us or request a quotation in your private area.The Dragon license agreement is available (PDF file), please read it carefully for details about the above mentioned options.
Dragon can be purchased on our website (payment by bank transfer or directly on-line with credit cards) and the software is delivered by a safe download procedure. Please register on our website and log in, a form for quotation request is available in your private area. If you wish you can contact us directly by email to request a quotation or further details about licensing/pricing schemes.
Several worldwide distributors are also available. It is possible to purchase Dragon at the same conditions reported in these pages from any of the following distributors:
CHINA Tri-I Biotech
JAPAN Affinity Science Corporation
POLAND FQS Poland Sp. z o.o.
SWISS CONFEDERATION SparkDynamic GmbH
TAIWAN Scientific Formosa Inc.
TURKEY LookUs Scientific